BDBM50220289 (R)-1-((2R,6R)-1-(4-chlorophenylsulfonyl)-6-propylpiperidin-2-yl)cyclopropyl 3-hydroxypyrrolidine-1-carboxylate::CHEMBL240285
SMILES CCC[C@@H]1CCC[C@@H](N1S(=O)(=O)c1ccc(Cl)cc1)C1(CC1)OC(=O)N1CC[C@@H](O)C1
InChI Key InChIKey=VCSMPFGNSZFRRW-QWFCFKBJSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50220289
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair