BDBM50220300 1-((2R,6R)-1-(3,4-difluorophenylsulfonyl)-6-ethylpiperidin-2-yl)cyclopropyl 8-(2-hydroxyethyl)-3,8-diaza-bicyclo[3.2.1]octane-3-carboxylate::CHEMBL236189
SMILES CC[C@@H]1CCC[C@@H](N1S(=O)(=O)c1ccc(F)c(F)c1)C1(CC1)OC(=O)N1CC2CCC(C1)N2CCO
InChI Key InChIKey=XWKRTKOWMQDAIK-VSILJMIMSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50220300
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair