BDBM50220304 1-((2R,6R)-6-ethyl-1-(4-fluorophenylsulfonyl)piperidin-2-yl)cyclopropyl 8-(2-hydroxyethyl)-3,8-diaza-bicyclo[3.2.1]octane-3-carboxylate::CHEMBL236186
SMILES CC[C@@H]1CCC[C@@H](N1S(=O)(=O)c1ccc(F)cc1)C1(CC1)OC(=O)N1CC2CCC(C1)N2CCO
InChI Key InChIKey=WMZBTZZLGWZIBX-ZDTVFLJBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50220304
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair