BDBM50221443 (2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE::(R)-3-amino-1-((R)-8-methyl-2-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one::CHEMBL250787

SMILES C[C@H]1N(CCn2nc(nc12)C(F)(F)F)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=FDEXEPZGMKFCTG-PSASIEDQSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50221443   

TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221443((2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHY...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221443((2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHY...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50221443((2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHY...)
Affinity DataIC50:  25nMAssay Description:Inhibition of dipeptidyl peptidase 4 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50221443((2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHY...)
Affinity DataIC50:  25nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221443((2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHY...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed