BDBM50221516 6-methoxy-7-(3-morpholinopropoxy)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile::CHEMBL248392
SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCOCC1)C#N
InChI Key InChIKey=NHWFEYYJOLZGNB-XUZZJYLKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50221516
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human EGFR autophosphorylation in A431 cellsMore data for this Ligand-Target Pair