BDBM50221518 6,7-dimethoxy-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile::CHEMBL248044
SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC
InChI Key InChIKey=VTTRFTSEAVQHSR-MAUKXSAKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50221518
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human EGFR autophosphorylation in A431 cellsMore data for this Ligand-Target Pair