BDBM50222098 CHEMBL93161
SMILES Fc1ccc(Sc2nc3CNC(=O)N(c3cc2N2CCN(CCN3CCCC3)CC2)c2c(Cl)cccc2Cl)c(F)c1
InChI Key InChIKey=RYMVWMWRYADLJC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50222098
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Anti human TNF-alpha activity determined through TNF-alpha release was measured in the supernatants by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of LPS-induced release of TNF-alpha from human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against mouse Mitogen-activated protein kinase p38More data for this Ligand-Target Pair