BDBM50222875 6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-(piperidin-3-ylmethyl)quinazolin-4(3H)-one::CHEMBL429817

SMILES Cc1ccccc1-c1nc2ccc(Oc3ccc(F)cc3)cc2c(=O)n1CC1CCCNC1

InChI Key InChIKey=FKNVILKOXAKHLQ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222875   

TargetGrowth hormone secretagogue receptor type 1(Ovis aries)
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50222875(6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-(piperidi...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50222875(6-(4-fluorophenoxy)-2-(2-methylphenyl)-3-(piperidi...)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at human recombinant GHSR1a expressed in HEK293F cells assessed as stimulation of [35S]GTP-gamma-S binding relative to ghrelinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed