BDBM50223034 3,6-diethyl-5-(3-methylpyridin-2-yloxy)-N-(1-phenylpropyl)pyrazin-2-amine::CHEMBL248816

SMILES CCC(Nc1nc(CC)c(Oc2ncccc2C)nc1CC)c1ccccc1

InChI Key InChIKey=BCBJNWHOTOYKGN-UHFFFAOYSA-N

Data  1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223034   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer Inc

Curated by ChEMBL
LigandPNGBDBM50223034(3,6-diethyl-5-(3-methylpyridin-2-yloxy)-N-(1-pheny...)
Show SMILES CCC(Nc1nc(CC)c(Oc2ncccc2C)nc1CC)c1ccccc1
Show InChI InChI=1S/C23H28N4O/c1-5-18(17-13-9-8-10-14-17)25-21-19(6-2)27-23(20(7-3)26-21)28-22-16(4)12-11-15-24-22/h8-15,18H,5-7H2,1-4H3,(H,25,26)
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of [125I]Tyr-o-CRF from CRF1 receptor in IMR32 cellsMore data for this Ligand-Target Pair