BDBM50224357 4-amino-2-(4-fluoro-phenyl)-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one::CHEMBL235071

SMILES Nc1nc2ccccc2n2n1nc(-c1ccc(F)cc1)c2=O

InChI Key InChIKey=AWWNWZTXVQGOOY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50224357   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224357(4-amino-2-(4-fluoro-phenyl)-3,3a,5,9b-tetraaza-cyc...)
Affinity DataKi:  20.1nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224357(4-amino-2-(4-fluoro-phenyl)-3,3a,5,9b-tetraaza-cyc...)
Affinity DataKi:  65.2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50224357(4-amino-2-(4-fluoro-phenyl)-3,3a,5,9b-tetraaza-cyc...)
Affinity DataKi:  369nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50224357(4-amino-2-(4-fluoro-phenyl)-3,3a,5,9b-tetraaza-cyc...)
Affinity DataKi:  369nMAssay Description:Displacement of [3H]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed