BDBM50224883 7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,16-dioxa-2,4,19,21-tetraaza-tricyclo[15.3.1.0*5,10*]henicosa-1(21),5,7,9,17,19-hexaene-18-crbonitrile::CHEMBL248757
SMILES Clc1cc2NC(=O)Nc3cnc(C#N)c(OCCCCOc2cc1NCc1cncs1)n3
InChI Key InChIKey=AZTMYWWWILJAKW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 110 hits for monomerid = 50224883
Affinity DataKi: 911nMAssay Description:Inhibition of GSK3 alphaMore data for this Ligand-Target Pair
Affinity DataKi: 1.12E+3nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
Affinity DataKi: >1.39E+3nMAssay Description:Inhibition of ZIPkMore data for this Ligand-Target Pair
Affinity DataKi: >1.42E+3nMAssay Description:Inhibition of PIM2More data for this Ligand-Target Pair
Affinity DataKi: >1.44E+3nMAssay Description:Inhibition of ERBB2More data for this Ligand-Target Pair
Affinity DataKi: >1.44E+3nMAssay Description:Inhibition of STK31More data for this Ligand-Target Pair
Affinity DataKi: >1.45E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit PRKX(Human)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >1.49E+3nMAssay Description:Inhibition of PRKXMore data for this Ligand-Target Pair
Affinity DataKi: >1.50E+3nMAssay Description:Inhibition of ARK5More data for this Ligand-Target Pair
Affinity DataKi: >1.52E+3nMAssay Description:Inhibition of WNK2More data for this Ligand-Target Pair
Affinity DataKi: >1.53E+3nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
Affinity DataKi: >1.53E+3nMAssay Description:Inhibition of TBK1More data for this Ligand-Target Pair
Affinity DataKi: >1.53E+3nMAssay Description:Inhibition of PRAKMore data for this Ligand-Target Pair
Affinity DataKi: >1.53E+3nMAssay Description:Inhibition of TSSK2More data for this Ligand-Target Pair
Affinity DataKi: >1.55E+3nMAssay Description:Inhibition of CDK6More data for this Ligand-Target Pair
Affinity DataKi: >1.55E+3nMAssay Description:Inhibition of NEK11More data for this Ligand-Target Pair
Affinity DataKi: >1.60E+3nMAssay Description:Inhibition of TSSK1More data for this Ligand-Target Pair
Affinity DataKi: >1.64E+3nMAssay Description:Inhibition of STK33More data for this Ligand-Target Pair
Affinity DataKi: >1.64E+3nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
Affinity DataKi: >1.65E+3nMAssay Description:Inhibition of MUSKMore data for this Ligand-Target Pair
Affinity DataKi: >1.67E+3nMAssay Description:Inhibition of NEK3More data for this Ligand-Target Pair
Affinity DataKi: >1.67E+3nMAssay Description:Inhibition of MLK1More data for this Ligand-Target Pair
Affinity DataKi: >1.68E+3nMAssay Description:Inhibition of CAMK1More data for this Ligand-Target Pair
Affinity DataKi: >1.72E+3nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
Affinity DataKi: >1.74E+3nMAssay Description:Inhibition of MSSK1More data for this Ligand-Target Pair
Affinity DataKi: >1.80E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
Affinity DataKi: >1.86E+3nMAssay Description:Inhibition of FGFR3More data for this Ligand-Target Pair
Affinity DataKi: >1.89E+3nMAssay Description:Inhibition of MSK1More data for this Ligand-Target Pair
Affinity DataKi: >1.94E+3nMAssay Description:Inhibition of TYK2More data for this Ligand-Target Pair
Affinity DataKi: 2.31E+3nMAssay Description:Inhibition of SRPK1More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >2.34E+3nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
Affinity DataKi: >2.48E+3nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
Affinity DataKi: >2.48E+3nMAssay Description:Inhibition of TRKAMore data for this Ligand-Target Pair
Affinity DataKi: 3.01E+3nMAssay Description:Inhibition of IRAK1More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of DYRK1AMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL