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BDBM50224964 3-(6-tert-butyl-2-oxo-2H-chromen-3-yl)-N-hydroxypropanamide::CHEMBL402991

SMILES: CC(C)(C)c1ccc2oc(=O)c(CCC(=O)NO)cc2c1

InChI Key: InChIKey=OMHMZZGGFHEFEP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224964   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Disintegrin and metalloproteinase domain-containing protein 17


(Homo sapiens (Human))
BDBM50224964
PNG
(3-(6-tert-butyl-2-oxo-2H-chromen-3-yl)-N-hydroxypr...)
Show SMILES CC(C)(C)c1ccc2oc(=O)c(CCC(=O)NO)cc2c1
Show InChI InChI=1S/C16H19NO4/c1-16(2,3)12-5-6-13-11(9-12)8-10(15(19)21-13)4-7-14(18)17-20/h5-6,8-9,20H,4,7H2,1-3H3,(H,17,18)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.24E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Inhibition of human TACE


Bioorg Med Chem 16: 530-5 (2008)


Article DOI: 10.1016/j.bmc.2007.09.014
BindingDB Entry DOI: 10.7270/Q2QF8SM7
More data for this
Ligand-Target Pair