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BDBM50225504 EHT-0202::ETAZOLATE::Etazolate::SQ-20009

SMILES: [#6]-[#6]-[#8]-[#6](=O)-c1cnc2n(-[#6]-[#6])ncc2c1-[#7]\[#7]=[#6](\[#6])-[#6]

InChI Key: InChIKey=OPQRBXUBWHDHPQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225504   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 3


(Homo sapiens (Human))
BDBM50225504
PNG
(EHT-0202 | ETAZOLATE | Etazolate | SQ-20009)
Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NN=C(C)C
Show InChI InChI=1S/C14H19N5O2/c1-5-19-13-10(8-16-19)12(18-17-9(3)4)11(7-15-13)14(20)21-6-2/h7-8H,5-6H2,1-4H3,(H,15,18)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
1.20E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity for low Km cAMP phosphodiesterase PDE III of sheep lung


J Med Chem 28: 537-45 (1985)


Article DOI: 10.1021/jm50001a001
BindingDB Entry DOI: 10.7270/Q2N58MXT
More data for this
Ligand-Target Pair
Phosphodiesterase 1


(Homo sapiens (Human))
BDBM50225504
PNG
(EHT-0202 | ETAZOLATE | Etazolate | SQ-20009)
Show SMILES CCOC(=O)c1cnc2n(CC)ncc2c1NN=C(C)C
Show InChI InChI=1S/C14H19N5O2/c1-5-19-13-10(8-16-19)12(18-17-9(3)4)11(7-15-13)14(20)21-6-2/h7-8H,5-6H2,1-4H3,(H,15,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity for [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of sheep lung


J Med Chem 28: 537-45 (1985)


Article DOI: 10.1021/jm50001a001
BindingDB Entry DOI: 10.7270/Q2N58MXT
More data for this
Ligand-Target Pair