BDBM50226445 2-amino-6-[2-(1H-indol-6-yl)ethyl]pyrimidin-4(3H)-one::CHEMBL236777

SMILES Nc1nc(CCc2ccc3cc[nH]c3c2)cc(=O)[nH]1

InChI Key InChIKey=VRAZIAJSKFRSIP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226445   

TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226445(2-amino-6-[2-(1H-indol-6-yl)ethyl]pyrimidin-4(3H)-...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibition of BACE1 by SPR assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226445(2-amino-6-[2-(1H-indol-6-yl)ethyl]pyrimidin-4(3H)-...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair