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BDBM50227089 CHEMBL173279

SMILES: CCCCCCc1ccc(\C=C\C(=O)Nc2cccc3OCC(Oc23)c2nnn[nH]2)cc1

InChI Key: InChIKey=PWEJTHONIDHCLI-CCEZHUSRSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227089   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cysteinyl leukotriene receptor


(Homo sapiens (Human))
BDBM50227089
PNG
(CHEMBL173279)
Show SMILES CCCCCCc1ccc(\C=C\C(=O)Nc2cccc3OCC(Oc23)c2nnn[nH]2)cc1
Show InChI InChI=1S/C24H27N5O3/c1-2-3-4-5-7-17-10-12-18(13-11-17)14-15-22(30)25-19-8-6-9-20-23(19)32-21(16-31-20)24-26-28-29-27-24/h6,8-15,21H,2-5,7,16H2,1H3,(H,25,30)(H,26,27,28,29)/b15-14+
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Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileum


J Med Chem 31: 84-91 (1988)


Article DOI: 10.1021/jm00396a013
BindingDB Entry DOI: 10.7270/Q20K2BSP
More data for this
Ligand-Target Pair