BDBM50228442 4-(2-aminophenylthio)-3-((dimethylamino)methyl)phenol::CHEMBL241228

SMILES CN(C)Cc1cc(O)ccc1Sc1ccccc1N

InChI Key InChIKey=WTZRMYOBIYKNQJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50228442   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228442(4-(2-aminophenylthio)-3-((dimethylamino)methyl)phe...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228442(4-(2-aminophenylthio)-3-((dimethylamino)methyl)phe...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]-iodonisoxetine from NET expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228442(4-(2-aminophenylthio)-3-((dimethylamino)methyl)phe...)
Affinity DataKi:  659nMAssay Description:Displacement of [125I]N-(3'-iodopropen-2'yl)-2-beta-carbomethoxy-3-beta-(4-chlorophenyl)tropane from DAT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed