BDBM50228753 (S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-((R)-3-phenyl-2-phenylmethanesulfonylamino-propionylamino)-succinamide::(S)-N1-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-yl)-2-((R)-3-phenyl-2-(phenylmethylsulfonamido)propanamido)succinamide::CHEMBL257867

SMILES [#7]-[#6](=O)-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-c1ccccc1)-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-c1nccs1

InChI Key InChIKey=IOTMESNHTFSKOB-RJGXRXQPSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50228753   

TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed