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BDBM50228852 CHEMBL353471

SMILES: COc1ccccc1Oc1ncccc1C(=O)NCc1ccccc1

InChI Key: InChIKey=LWTUWJATXJDMMX-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228852   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228852
PNG
(CHEMBL353471)
Show SMILES COc1ccccc1Oc1ncccc1C(=O)NCc1ccccc1
Show InChI InChI=1S/C20H18N2O3/c1-24-17-11-5-6-12-18(17)25-20-16(10-7-13-21-20)19(23)22-14-15-8-3-2-4-9-15/h2-13H,14H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]cAMP (NEN NET-275) binding to Calcium-Independent Phosphodiesterase from rat brain.


J Med Chem 34: 86-9 (1991)


Article DOI: 10.1021/jm00105a015
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228852
PNG
(CHEMBL353471)
Show SMILES COc1ccccc1Oc1ncccc1C(=O)NCc1ccccc1
Show InChI InChI=1S/C20H18N2O3/c1-24-17-11-5-6-12-18(17)25-20-16(10-7-13-21-20)19(23)22-14-15-8-3-2-4-9-15/h2-13H,14H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]rolipram binding to rat brain membranes.


J Med Chem 34: 86-9 (1991)


Article DOI: 10.1021/jm00105a015
More data for this
Ligand-Target Pair