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BDBM50228858 CHEMBL169003

SMILES: Fc1ccc(Oc2ncccc2C(=O)NCc2ccccc2)cc1

InChI Key: InChIKey=KFZXYYHZDWJVJE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228858   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228858
PNG
(CHEMBL169003)
Show SMILES Fc1ccc(Oc2ncccc2C(=O)NCc2ccccc2)cc1
Show InChI InChI=1S/C19H15FN2O2/c20-15-8-10-16(11-9-15)24-19-17(7-4-12-21-19)18(23)22-13-14-5-2-1-3-6-14/h1-12H,13H2,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]cAMP (NEN NET-275) binding to Calcium-Independent Phosphodiesterase from rat brain.


J Med Chem 34: 86-9 (1991)


Article DOI: 10.1021/jm00105a015
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228858
PNG
(CHEMBL169003)
Show SMILES Fc1ccc(Oc2ncccc2C(=O)NCc2ccccc2)cc1
Show InChI InChI=1S/C19H15FN2O2/c20-15-8-10-16(11-9-15)24-19-17(7-4-12-21-19)18(23)22-13-14-5-2-1-3-6-14/h1-12H,13H2,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.70E+4n/an/an/an/an/an/a



Pfizer Central Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]rolipram binding to rat brain membranes.


J Med Chem 34: 86-9 (1991)


Article DOI: 10.1021/jm00105a015
More data for this
Ligand-Target Pair