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BDBM50228860 CHEMBL169474

SMILES: CC(C)NC(=O)c1cccnc1Oc1ccc(F)cc1

InChI Key: InChIKey=JAFMQAZQUFBGLB-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228860   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228860
PNG
(CHEMBL169474)
Show SMILES CC(C)NC(=O)c1cccnc1Oc1ccc(F)cc1
Show InChI InChI=1S/C15H15FN2O2/c1-10(2)18-14(19)13-4-3-9-17-15(13)20-12-7-5-11(16)6-8-12/h3-10H,1-2H3,(H,18,19)
GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of [3H]cAMP (NEN NET-275) binding to Calcium-Independent Phosphodiesterase from rat brain.


Citation and Details

Article DOI: 10.1021/jm00105a015
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228860
PNG
(CHEMBL169474)
Show SMILES CC(C)NC(=O)c1cccnc1Oc1ccc(F)cc1
Show InChI InChI=1S/C15H15FN2O2/c1-10(2)18-14(19)13-4-3-9-17-15(13)20-12-7-5-11(16)6-8-12/h3-10H,1-2H3,(H,18,19)
GoogleScholar
AffyNet 
UniChem
Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of [3H]rolipram binding to rat brain membranes.


Citation and Details

Article DOI: 10.1021/jm00105a015
More data for this
Ligand-Target Pair