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BDBM50229503 CHEMBL309651

SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)CCc1ccc(O)cc1)C(C)C)C(O)=O

InChI Key: InChIKey=ZARWDFNQMSFZAM-CADLLZAKSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229503   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50229503
PNG
(CHEMBL309651)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)CCc1ccc(O)cc1)C(C)C)C(O)=O
Show InChI InChI=1S/C31H44N6O7/c1-5-19(4)27(31(43)44)36-28(40)24-7-6-14-37(24)30(42)23(15-21-16-32-17-33-21)34-29(41)26(18(2)3)35-25(39)13-10-20-8-11-22(38)12-9-20/h8-9,11-12,16-19,23-24,26-27,38H,5-7,10,13-15H2,1-4H3,(H,32,33)(H,34,41)(H,35,39)(H,36,40)(H,43,44)/t19-,23-,24-,26-,27-/m0/s1
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Article
PubMed
n/an/a>1.50E+4n/an/an/an/an/an/a



Berlex Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity as antagonist of AII on guinea pig ileum


J Med Chem 34: 2402-10 (1991)


Article DOI: 10.1021/jm00112a014
More data for this
Ligand-Target Pair