BDBM50229641 CHEMBL400528::pyrrolidin-3-yl 4-((4-(4-cyano-2-methylphenyl)piperidin-1-ylsulfonyl)methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate
SMILES Cc1cc(ccc1C1CCN(CC1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC1CCNC1)C(=O)NO)C#N
InChI Key InChIKey=GHULRYOEOZAXEG-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50229641
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair