BDBM50229656 CHEMBL252612::pyrrolidin-3-yl 4-(hydroxycarbamoyl)-4-((4-o-tolylpiperidin-1-ylsulfonyl)methyl)piperidine-1-carboxylate

SMILES Cc1ccccc1C1CCN(CC1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC1CCNC1)C(=O)NO

InChI Key InChIKey=PWJXCFJUGNPSAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229656   

LigandPNGBDBM50229656(CHEMBL252612 | pyrrolidin-3-yl 4-(hydroxycarbamoyl...)
Affinity DataIC50:  18nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229656(CHEMBL252612 | pyrrolidin-3-yl 4-(hydroxycarbamoyl...)
Affinity DataIC50:  546nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229656(CHEMBL252612 | pyrrolidin-3-yl 4-(hydroxycarbamoyl...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50229656(CHEMBL252612 | pyrrolidin-3-yl 4-(hydroxycarbamoyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed