BDBM50229897 CHEMBL314007

SMILES Cc1cc(N)c2cc(NC(=O)\C=C\c3ccccc3C(F)(F)F)ccc2n1

InChI Key InChIKey=VALGCIZQXXKDDI-RMKNXTFCSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229897   

TargetMyeloperoxidase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229897(CHEMBL314007)
Affinity DataEC50: <3.00E+3nMAssay Description:Compound was tested for the induction of nonspecific myeloperoxidase (MPO) releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229897(CHEMBL314007)
Affinity DataIC50:  2.42E+4nMAssay Description:Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed