BDBM50229897 CHEMBL314007
SMILES Cc1cc(N)c2cc(NC(=O)\C=C\c3ccccc3C(F)(F)F)ccc2n1
InChI Key InChIKey=VALGCIZQXXKDDI-RMKNXTFCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50229897
TargetMyeloperoxidase(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: <3.00E+3nMAssay Description:Compound was tested for the induction of nonspecific myeloperoxidase (MPO) releaseMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.42E+4nMAssay Description:Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.More data for this Ligand-Target Pair