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BDBM50229905 CHEMBL315313

SMILES: Cc1cc(N)c2cc(NC(=O)c3ccc4ccccc4c3)ccc2n1

InChI Key: InChIKey=NHHXKPVASDNEHN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229905   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor


(Homo sapiens (Human))
BDBM50229905
PNG
(CHEMBL315313)
Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccc4ccccc4c3)ccc2n1
Show InChI InChI=1S/C21H17N3O/c1-13-10-19(22)18-12-17(8-9-20(18)23-13)24-21(25)16-7-6-14-4-2-3-5-15(14)11-16/h2-12H,1H3,(H2,22,23)(H,24,25)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a


TBA

Assay Description
Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.


Citation and Details

Article DOI: 10.1021/jm00080a008
More data for this
Ligand-Target Pair