BDBM50231037 CHEMBL253054::sodium (3R,5R)-7-(3-(azetidin-1-ylsulfonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

SMILES CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N1CCC1

InChI Key InChIKey=BQXHXGRMRBSNNL-DNQXCXABSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231037   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50231037(CHEMBL253054 | sodium (3R,5R)-7-(3-(azetidin-1-yls...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed