BDBM50231682 CHEMBL251862::N-((2S,3R)-4-((S)-1-(cyclohexylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-phenylbutan-2-yl)-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide
SMILES CCNc1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN[C@@H](C)C(=O)NC1CCCCC1)N1CCCC1=O
InChI Key InChIKey=ARWMRRUIIHCDKG-PWUSVURUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50231682
Affinity DataIC50: 310nMAssay Description:Inhibition of BACE1 assessed as beta amyloid 40 production by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of BACE1 expressed in SHSY5Y cells assessed as reduction of amyloid beta 40 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of BACE1 expressed in SHSY5Y cells assessed as reduction of amyloid beta 42 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 307nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 363nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of BACE1 assessed as beta amyloid 42 production by cell based assayMore data for this Ligand-Target Pair