BDBM50232749 CHEMBL4095749::US11046670, Table 6.5

SMILES [H][C@]12C[C@@]([H])(N(CC1)C(=O)OCc1ccccc1)c1cc(ccc21)N1CCN(CC(C)=C)CC1

InChI Key InChIKey=RIDKTDMXJSXQEJ-ATIYNZHBSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50232749   

TargetSigma intracellular receptor 2(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50232749(CHEMBL4095749 | US11046670, Table 6.5)
Affinity DataKi:  17.5nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50232749(CHEMBL4095749 | US11046670, Table 6.5)
Affinity DataKi:  17.5nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50232749(CHEMBL4095749 | US11046670, Table 6.5)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells in presence of (+)-pentazocine by PDSP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50232749(CHEMBL4095749 | US11046670, Table 6.5)
Affinity DataKi:  413nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50232749(CHEMBL4095749 | US11046670, Table 6.5)
Affinity DataKi:  413nMAssay Description:Receptor binding assays were performed by the Psychoactive Drug Screening Program (PDSP) at Chapel Hill, N.C. The assay protocol book can be accessed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM50232749(CHEMBL4095749 | US11046670, Table 6.5)
Affinity DataKi:  430nMAssay Description:Receptor binding assays were performed by the Psychoactive Drug Screening Program (PDSP) at Chapel Hill, N.C. The assay protocol book can be accessed...More data for this Ligand-Target Pair
In DepthDetails US Patent