BDBM50233430 CHEMBL3955791::US11207302, Example 2

SMILES CS(=O)(=O)NCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=UCDYISCEVMDSNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233430   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50233430(CHEMBL3955791 | US11207302, Example 2)
Affinity DataIC50:  16nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50233430(CHEMBL3955791 | US11207302, Example 2)
Affinity DataIC50: <200nMAssay Description:Human indoleamine 2,3-dioxygenasae (IDO) with an N-terminal His tag was expressed in E. coli and purified to homogeneity. IDO catalyzes the oxidative...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50233430(CHEMBL3955791 | US11207302, Example 2)
Affinity DataIC50:  100nMAssay Description:Inhibition of human N-terminal His-tagged IDO1 expressed in Escherichia coli using D-Trp as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed