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BDBM50233709 CHEMBL253027::N-(4-(1H-imidazol-1-yl)-2-(piperidin-1-yl)phenyl)-5-cyanofuran-2-carboxamide

SMILES: O=C(Nc1ccc(cc1N1CCCCC1)-n1ccnc1)c1ccc(o1)C#N

InChI Key: InChIKey=ZRIOTTIHUCWFGP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233709   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50233709
PNG
(CHEMBL253027 | N-(4-(1H-imidazol-1-yl)-2-(piperidi...)
Show SMILES O=C(Nc1ccc(cc1N1CCCCC1)-n1ccnc1)c1ccc(o1)C#N
Show InChI InChI=1S/C20H19N5O2/c21-13-16-5-7-19(27-16)20(26)23-17-6-4-15(25-11-8-22-14-25)12-18(17)24-9-2-1-3-10-24/h4-8,11-12,14H,1-3,9-10H2,(H,23,26)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarization


Bioorg Med Chem Lett 18: 1642-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.059
BindingDB Entry DOI: 10.7270/Q2FB52PS
More data for this
Ligand-Target Pair