BDBM50236176 CHEMBL4065677

SMILES CCCCNc1nc(N)nc(C)c1Cc1ccccc1

InChI Key InChIKey=PAZGTLUPBJUMGJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236176   

TargetToll-like receptor 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50236176(CHEMBL4065677)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50236176(CHEMBL4065677)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed