BDBM50236375 (S)-2-(4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)quinazolin-5-yloxy)-N,N-dimethylpropanamide::CHEMBL256784

SMILES C[C@H](Oc1cccc2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12)C(=O)N(C)C

InChI Key InChIKey=BBJFDODASSZYKE-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236375   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50236375((S)-2-(4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human erbB2 autophosphorylation in MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed