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BDBM50236791 CHEMBL4066047

SMILES: COc1ccc2c(CN3CCN(C)CC3)cn(c2c1)S(=O)(=O)c1ccc(cc1)C(C)C

InChI Key: InChIKey=FSPVKGBRVGTTAB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236791   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50236791
PNG
(CHEMBL4066047)
Show SMILES COc1ccc2c(CN3CCN(C)CC3)cn(c2c1)S(=O)(=O)c1ccc(cc1)C(C)C
Show InChI InChI=1S/C24H31N3O3S/c1-18(2)19-5-8-22(9-6-19)31(28,29)27-17-20(16-26-13-11-25(3)12-14-26)23-10-7-21(30-4)15-24(23)27/h5-10,15,17-18H,11-14,16H2,1-4H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
36n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins


J Med Chem 60: 1843-1859 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01662
BindingDB Entry DOI: 10.7270/Q27S7R1X
More data for this
Ligand-Target Pair