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BDBM50236800 CHEMBL4100818

SMILES: CN1CCN(Cc2cn(c3ccccc23)S(=O)(=O)c2cccc(Br)c2)CC1

InChI Key: InChIKey=DWXNTRPXHMRBJM-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236800   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50236800
PNG
(CHEMBL4100818)
Show SMILES CN1CCN(Cc2cn(c3ccccc23)S(=O)(=O)c2cccc(Br)c2)CC1
Show InChI InChI=1S/C20H22BrN3O2S/c1-22-9-11-23(12-10-22)14-16-15-24(20-8-3-2-7-19(16)20)27(25,26)18-6-4-5-17(21)13-18/h2-8,13,15H,9-12,14H2,1H3
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PC cid
PC sid
UniChem

Similars

Article
PubMed
19n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Agonist efficacy as effective concentration to stimulate binding of [35S]GTP-gamma-S, by activation of human A3AR receptor


J Med Chem 60: 1843-1859 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01662
BindingDB Entry DOI: 10.7270/Q27S7R1X
More data for this
Ligand-Target Pair