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BDBM50236802 CHEMBL4098815

SMILES: CN1CCN(Cc2cn(c3cccc(Cl)c23)S(=O)(=O)c2ccc(F)cc2)CC1

InChI Key: InChIKey=JCSWACODFGEOAL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236802   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50236802
PNG
(CHEMBL4098815)
Show SMILES CN1CCN(Cc2cn(c3cccc(Cl)c23)S(=O)(=O)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C20H21ClFN3O2S/c1-23-9-11-24(12-10-23)13-15-14-25(19-4-2-3-18(21)20(15)19)28(26,27)17-7-5-16(22)6-8-17/h2-8,14H,9-13H2,1H3
Reactome pathway
KEGG

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
31n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 mins


J Med Chem 60: 1843-1859 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01662
BindingDB Entry DOI: 10.7270/Q27S7R1X
More data for this
Ligand-Target Pair