BDBM50237845 CHEMBL258040::N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-1H-INDAZOL-3-YL]-2-(4-PIPERIDIN-1-YLPHENYL)ACETAMIDE::N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H-indazol-3-yl]-2-(4-piperidin-1-yl-phenyl)-acetamide

SMILES O=C(Cc1ccc(cc1)N1CCCCC1)Nc1n[nH]c2ccc(cc12)N1CCCS1(=O)=O

InChI Key InChIKey=ZXYIRNXOAJYLCU-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237845   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237845(CHEMBL258040 | N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-Y...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237845(CHEMBL258040 | N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-Y...)
Affinity DataIC50:  150nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237845(CHEMBL258040 | N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-Y...)
Affinity DataIC50:  750nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed