BDBM50238386 CHEMBL4068548

SMILES Nc1nc(cn2c1nn(-c1ccccc1)c2=O)-c1cccc(O)c1

InChI Key InChIKey=KRTWVDXLRBRAQC-UHFFFAOYSA-N

Data  7 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50238386   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]CCPA from human adenosine receptor A1 expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataKi:  134nMAssay Description:Inhibition of 5-HT uptake in synaptosomal preparation from rat corpus striatum, using [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataKi:  9.30E+4nMAssay Description:Inhibition of human CA2 incubated for 15 mins by stopped- flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA9 incubated for 15 mins by stopped- flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA1 incubated for 15 mins by stopped- flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA12 incubated for 15 mins by stopped- flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human A2B receptor expressed in CHO cell membrane assessed as reduction in NECA-stimulated AMP level by GloSensor CAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238386(CHEMBL4068548)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human adenosine receptor A2B expressed in CHO cell membranes assessed as inhibition of NECA-induced increase of cAMP accumulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed