BDBM50240885 CHEMBL4064010
SMILES O=c1cc(OCc2cccc(c2)C#N)nc2COC[C@@H](Cc3ccccc3)n12
InChI Key InChIKey=TWXFCHIWVYOCEG-LJQANCHMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50240885
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]MPEPy from human mGlu5 expressed in HEK293FT cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of rat mGlu5 expressed in HEK293 cells assessed as inhibition of glutamate-induced intracellular calcium accumulation ...More data for this Ligand-Target Pair