BDBM50240981 4'-piperazin-1-yl-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide::CHEMBL371133
SMILES O=C(NC1(CCCCC1)C(=O)NCC#N)c1ccc(cc1)-c1ccc(cc1)N1CCNCC1
InChI Key InChIKey=ZDEDZSBCUXOIBZ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50240981
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 614nMAssay Description:Inhibitory activity against cathepsin B from humanMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against cathepsin K using humanized rabbit enzymeMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibitory activity against cathepsin L from humanMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against cathepsin S from humanMore data for this Ligand-Target Pair