BDBM50241642 (+)-Obaberine::CHEMBL451211::CHEMBL464525::Obaberine

SMILES COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(Oc5c(OC)c(OC)cc6CCN(C)[C@@H](Cc7ccc(Oc1c2)cc7)c56)cc34

InChI Key InChIKey=FBCXFKWMGIWMJQ-IHLOFXLRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241642   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50241642((+)-Obaberine | CHEMBL451211 | CHEMBL464525 | Obab...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50241642((+)-Obaberine | CHEMBL451211 | CHEMBL464525 | Obab...)
Affinity DataIC50:  2.84E+4nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Wistar rat striatal membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50241642((+)-Obaberine | CHEMBL451211 | CHEMBL464525 | Obab...)
Affinity DataIC50:  3.91E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in Wistar rat striatal membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed