BDBM50241957 CHEMBL4100650

SMILES FC(F)(F)c1cc(Cl)cc(N\N=C(/C#N)C(=O)c2cc(on2)-c2ccco2)c1

InChI Key InChIKey=ASXMOJVUQQDEAB-ZMOGYAJESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241957   

TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241957(CHEMBL4100650)
Affinity DataIC50:  3.60E+3nMAssay Description:In vito concentration required to displace [3H]cyclofoxy (Kd = 0.8 nM and concentration is 1.3 nM) from mu and kappa2 receptor in rat brain membranes...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241957(CHEMBL4100650)
Affinity DataIC50:  2.20E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed