BDBM50241966 CHEMBL4092921

SMILES COc1ccc(cc1)-c1cc(no1)C(=O)C(=N\Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)\C#N

InChI Key InChIKey=OPHHSQOWPLYZDG-OCSSWDANSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241966   

TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241966(CHEMBL4092921)
Affinity DataIC50:  5.60E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 4(Mus musculus)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50241966(CHEMBL4092921)
Affinity DataIC50:  7.00E+3nMAssay Description:Antagonist activity at mouse EPAC2 assessed as inhibition of EPAC2-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide exchange activity by 8-NB...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed