BDBM50242207 CHEMBL455364::Mangiferin

SMILES OC[C@H]1O[C@@H](Oc2c(O)cc3oc4cc(O)c(O)cc4c(=O)c3c2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key InChIKey=TXKFRRCKZWJXBW-GPRNFGOXSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50242207   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
University Of Delaware

LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  8.90E+3nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
University Of Delaware

LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  5.26E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L5(Homo sapiens (Human))
University Of Delaware

LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  3.00E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase(Clostridium perfringens)
Graduate School Of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 15(Homo sapiens (Human))
University Of Delaware

LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  5.66E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of aldose reductase in rat lens homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase, glycosomal(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  1.49E+5nMAssay Description:Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
University Of Delaware

LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  6.78E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed