BDBM50242582 4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-cyclohexylpiperazine-1-carboxamide::4-[(4-Chlorophenyl)(2,4-dichlorophenyl)methyl]-Ncyclohexylpiperazine-1-carboxamide::CHEMBL529436

SMILES Clc1ccc(cc1)C(N1CCN(CC1)C(=O)NC1CCCCC1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=QOSVXCGYSOHDAF-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50242582   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50242582(4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-c...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cells after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50242582(4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-c...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in CHO cells after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50242582(4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-c...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP55940-induced Ca2+ ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50242582(4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-c...)
Affinity DataIC50:  367nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHOK1 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Central Research Institute

Curated by ChEMBL
LigandPNGBDBM50242582(4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-c...)
Affinity DataIC50:  104nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebella membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50242582(4-((4-Chlorophenyl)(2,4-dichlorophenyl)methyl)-N-c...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]WIN55212-2 from human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed