BDBM50243206 CHEMBL486236::cis-N,N-diethyl-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine

SMILES CCN(CC)[C@@H]1C[C@H](Oc2ccccc2C)c2ccccc12

InChI Key InChIKey=VQTWAJKQIHYINF-QUCCMNQESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243206   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243206(CHEMBL486236 | cis-N,N-diethyl-3-(o-tolyloxy)-2,3-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243206(CHEMBL486236 | cis-N,N-diethyl-3-(o-tolyloxy)-2,3-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243206(CHEMBL486236 | cis-N,N-diethyl-3-(o-tolyloxy)-2,3-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed