BDBM50243588 CHEMBL4067800

SMILES CCCCS(=O)(=O)Oc1ccc(cc1)-n1c(C)c(nc1-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1

InChI Key InChIKey=HIILKHHEWYWFGN-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243588   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50243588(CHEMBL4067800)
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in beta-galactosidase expressing CHOK1 cell membranes after 60 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50243588(CHEMBL4067800)
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1 receptor expressed in beta-galactosidase expressing CHOK1 cell membranes after 60 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50243588(CHEMBL4067800)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at recombinant human CB1 receptor expressed in HEK293 cell membranes assessed as inhibition of CP55940-induced [35S]GTPgammaS bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50243588(CHEMBL4067800)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at recombinant human CB1 receptor expressed in HEK293 cell membranes assessed as inhibition of CP55940-induced [35S]GTPgammaS bin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed