BDBM50243601 (S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureido)-2-naphthamido)acetic acid::(S)-2-cyclohexyl-2-(3-(3-(2,6-dimethylphenyl)ureido)-2-naphthamido)acetic acid::CHEMBL459858

SMILES Cc1cccc(C)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N[C@@H](C1CCCCC1)C(O)=O

InChI Key InChIKey=LPGOCWBNYPXSCE-VWLOTQADSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243601   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243601((S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human glycogen phosphorylase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243601((S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureid...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of human liver glycogen phosphorylase A in HepG2 cells assessed as forskolin-induced glycogenolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243601((S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human liver glycogen phosphorylase A by fluorescence intensity endpoint assay in presence of glucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243601((S)-2-cyclohexyl-2-(2-(3-(2,6-dimethylphenyl)ureid...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human glycogen phosphorylase alpha in HepG2 cells assessed as inhibition of forskolin-induced glycogenolysis after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed