BDBM50243996 CHEMBL510375::N-Cycloheptyl-2-(4-isopropylpiperazine-1-yl)-6,7-dimethoxyquinazolin-4-amine

SMILES COc1cc2nc(nc(NC3CCCCCC3)c2cc1OC)N1CCN(CC1)C(C)C

InChI Key InChIKey=JQYVHNNWBJLLSC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243996   

TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243996(CHEMBL510375 | N-Cycloheptyl-2-(4-isopropylpiperaz...)
Affinity DataIC50:  660nMAssay Description:Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243996(CHEMBL510375 | N-Cycloheptyl-2-(4-isopropylpiperaz...)
Affinity DataIC50:  220nMAssay Description:Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed