BDBM50245513 2-(3-chlorophenoxy)-N-(1-((1-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide::CHEMBL471514

SMILES FC(F)(F)c1ccc(nc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1

InChI Key InChIKey=ADXBHAQACCRLQO-UHFFFAOYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245513   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
AstraZeneca R&D Mölndal

Curated by ChEMBL
LigandPNGBDBM50245513(2-(3-chlorophenoxy)-N-(1-((1-(5-(trifluoromethyl)p...)
Show SMILES FC(F)(F)c1ccc(nc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1
Show InChI InChI=1S/C24H24ClF3N4O2/c25-19-2-1-3-21(12-19)34-16-23(33)30-20-7-9-31(10-8-20)14-17-6-11-32(15-17)22-5-4-18(13-29-22)24(26,27)28/h1-6,11-13,15,20H,7-10,14,16H2,(H,30,33)
Affinity DataIC50: 92nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
AstraZeneca R&D Mölndal

Curated by ChEMBL
LigandPNGBDBM50245513(2-(3-chlorophenoxy)-N-(1-((1-(5-(trifluoromethyl)p...)
Show SMILES FC(F)(F)c1ccc(nc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1
Show InChI InChI=1S/C24H24ClF3N4O2/c25-19-2-1-3-21(12-19)34-16-23(33)30-20-7-9-31(10-8-20)14-17-6-11-32(15-17)22-5-4-18(13-29-22)24(26,27)28/h1-6,11-13,15,20H,7-10,14,16H2,(H,30,33)
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair