BDBM50245974 (rel)-(3-(4-fluorobenzyl)-8-(bis(2-chlorophenyl)methyl)-8-aza-bicyclo[3.2.1]octan-3-yl)methanamine::CHEMBL460093

SMILES NCC1(Cc2ccc(F)cc2)C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key InChIKey=BJUFPJMTZSDVBA-VXKWHMMOSA-N

Data  2 KI  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245974   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50245974((rel)-(3-(4-fluorobenzyl)-8-(bis(2-chlorophenyl)me...)
Show SMILES NCC1(Cc2ccc(F)cc2)C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl
Show InChI InChI=1S/C28H29Cl2FN2/c29-25-7-3-1-5-23(25)27(24-6-2-4-8-26(24)30)33-21-13-14-22(33)17-28(16-21,18-32)15-19-9-11-20(31)12-10-19/h1-12,21-22,27H,13-18,32H2/t21-,22-/m0/s1
Affinity DataKi:  34nMAssay Description:Displacement of [125I][Tyr14]nociceptin FQ from human cloned nociceptin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50245974((rel)-(3-(4-fluorobenzyl)-8-(bis(2-chlorophenyl)me...)
Show SMILES NCC1(Cc2ccc(F)cc2)C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl
Show InChI InChI=1S/C28H29Cl2FN2/c29-25-7-3-1-5-23(25)27(24-6-2-4-8-26(24)30)33-21-13-14-22(33)17-28(16-21,18-32)15-19-9-11-20(31)12-10-19/h1-12,21-22,27H,13-18,32H2/t21-,22-/m0/s1
Affinity DataKi:  1.41E+3nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50245974((rel)-(3-(4-fluorobenzyl)-8-(bis(2-chlorophenyl)me...)
Show SMILES NCC1(Cc2ccc(F)cc2)C[C@@H]2CC[C@@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl
Show InChI InChI=1S/C28H29Cl2FN2/c29-25-7-3-1-5-23(25)27(24-6-2-4-8-26(24)30)33-21-13-14-22(33)17-28(16-21,18-32)15-19-9-11-20(31)12-10-19/h1-12,21-22,27H,13-18,32H2/t21-,22-/m0/s1
Affinity DataEC50:  124nMAssay Description:Agonist activity at human cloned nociceptin receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair